Biomaterials and NanoFabrication

NanoInk's NanoFabrication Systems Division provides a new generation of Dip Pen Nanolithography® (DPN®) instrument systems for biomaterials and cell biology applications.

Nanoscale Biomaterials Printing

Printing of biomaterials at sub-cellular scales holds immense promise for studies in life sciences. The ability to create nanoscale patterns of DNA, proteins, lipids, biocompatible polymers and other biomaterials has the potential to revolutionize many areas of biological research and discovery, but until now the technology available to create these patterns has been overly complex, unacceptably slow, and unreliable.

NanoInk offers a new paradigm in nanoscale patterning systems for biomaterials studies.  Recent advances in Dip Pen Nanolithography technology make possible the direct deposition of biologically relevant molecules onto a variety of surfaces.  NanoInk’s DPN systems can reliably print features ranging in size from tens of nanometers to ten microns with nanoscale registry, all under ambient conditions.  These capabilities make the NanoInk platform an indispensable tool for biomaterials research in the life sciences area.

Benefits of Dip Pen Nanolithography (DPN):

• Pattern nano- to micron-sized features:                         

The ability to print a wide variety of biomaterials at sub-cellular levels enables researchers to address biologically relevant questions at the single cell level.  Miniaturization of capture domain sizes for use in biomarker detection applications leads to reduced assay times, smaller sample volume requirements and potentially higher sensitivity levels.

• Generate complex multiplexed patterns:

With capabilities to generate complex multiplexed patterns of biomaterials, scientists can simultaneously interrogate single cells with multiple materials and evaluate multiple targets in a single experiment.

• Achieve extremely precise, directed deposition:

NanoInk’s DPN systems can deposit relevant biomaterials at user defined locations with nanometer levels of precision.

Multiplexed protein deposition: 4 micron feature size and 16 micron pitch